The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol

The membrane activity of some saponins, such as digitonin or alpha-hederin, is usually attributed to their interaction with membrane cholesterol (Chol). This contrasts with our recent publication showing that Chol, contrary to sphingomyelin (SM), can delay the cytotoxicity of the saponin ginsenoside...

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Detalles Bibliográficos
Autores principales: Verstraeten, Sandrine L., Deleu, Magali, Janikowska-Sagan, Maria, Claereboudt, Emily J. S., Lins, Laurence, Tyteca, Donatienne, Mingeot-Leclercq, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513819/
https://www.ncbi.nlm.nih.gov/pubmed/31086211
http://dx.doi.org/10.1038/s41598-019-43674-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513819/
https://www.ncbi.nlm.nih.gov/pubmed/31086211
http://dx.doi.org/10.1038/s41598-019-43674-w

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