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Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity

The ubiquitous intracellular protease dipeptidyl peptidase 9 (DPP9) has roles in antigen presentation and B cell signaling. To investigate the importance of DPP9 in immune regeneration, primary and secondary chimeric mice were created in irradiated recipients using fetal liver cells and adult bone m...

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Detalles Bibliográficos
Autores principales: Gall, Margaret G., Zhang, Hui Emma, Lee, Quintin, Jolly, Christopher J., McCaughan, Geoffrey W., Cook, Adam, Roediger, Ben, Gorrell, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513830/
https://www.ncbi.nlm.nih.gov/pubmed/31086209
http://dx.doi.org/10.1038/s41598-019-43739-w