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Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus

Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation codons located up-stream from that adjacent to the predicted signal peptid...

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Detalles Bibliográficos
Autores principales: Cordero, Esteban M., Cortez, Cristian, Yoshida, Nobuko, da Silveira, José Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513831/
https://www.ncbi.nlm.nih.gov/pubmed/31086219
http://dx.doi.org/10.1038/s41598-019-43743-0