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Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB

Extracellular lysyl oxidases (LOX and LOXL1–LOXL4) are critical for collagen biosynthesis. LOXL2 is a marker of poor survival in oral squamous cell cancer. We investigated mechanisms by which tumor cell secreted LOXL2 targets proximal mesenchymal cells to enhance tumor growth and metastasis. This st...

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Detalles Bibliográficos
Autores principales:	Mahjour, Faranak, Dambal, Vrinda, Shrestha, Neha, Singh, Varun, Noonan, Vikki, Kantarci, Alpdogan, Trackman, Philip C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513832/ https://www.ncbi.nlm.nih.gov/pubmed/31086173 http://dx.doi.org/10.1038/s41389-019-0144-0

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