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Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis

Unfolded protein response (UPR) is an adaptive reaction for cells to reduce endoplasmic reticulum (ER) stress. In many types of cancers, such as lung cancer and pancreatic cancer, cancer cells may harness ER stress to facilitate their survival and growth. Prion protein (PrP) is a glycosylated cell s...

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Detalles Bibliográficos
Autores principales: Gao, Zhenxing, Peng, Min, Chen, Liang, Yang, Xiaowen, Li, Huan, Shi, Run, Wu, Guiru, Cai, Lili, Song, Qibin, Li, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513834/
https://www.ncbi.nlm.nih.gov/pubmed/31020572
http://dx.doi.org/10.1007/s12250-019-00107-2