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Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice

Pathological bone loss is caused by an imbalance between bone formation and resorption. The bone microenvironments are hypoxic, and hypoxia-inducible factor (HIF) is known to play notable roles in bone remodeling. However, the relevant functions of HIF-2α are not well understood. Here, we have shown...

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Detalles Bibliográficos
Autores principales: Lee, Sun Young, Park, Ka Hyon, Yu, Hyung-Gu, Kook, Eunbyul, Song, Won-Hyun, Lee, Gyuseok, Koh, Jeong-Tae, Shin, Hong-In, Choi, Je-Yong, Huh, Yun Hyun, Ryu, Je-Hwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513851/
https://www.ncbi.nlm.nih.gov/pubmed/31098335
http://dx.doi.org/10.1038/s41413-019-0054-y