A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

Hypoxia signaling plays a major role in non-malignant and malignant hyperproliferative diseases. Pulmonary hypertension (PH), a hypoxia-driven vascular disease, is characterized by a glycolytic switch similar to the Warburg effect in cancer. Ras association domain family 1A (RASSF1A) is a scaffold p...

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Detalles Bibliográficos
Autores principales: Dabral, Swati, Muecke, Christian, Valasarajan, Chanil, Schmoranzer, Mario, Wietelmann, Astrid, Semenza, Gregg L., Meister, Michael, Muley, Thomas, Seeger-Nukpezah, Tamina, Samakovlis, Christos, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Savai, Rajkumar, Pullamsetti, Soni S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513860/
https://www.ncbi.nlm.nih.gov/pubmed/31086178
http://dx.doi.org/10.1038/s41467-019-10044-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513860/
https://www.ncbi.nlm.nih.gov/pubmed/31086178
http://dx.doi.org/10.1038/s41467-019-10044-z

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