The structural basis of translational control by eIF2 phosphorylation

Protein synthesis in eukaryotes is controlled by signals and stresses via a common pathway, called the integrated stress response (ISR). Phosphorylation of the translation initiation factor eIF2 alpha at a conserved serine residue mediates translational control at the ISR core. To provide insight in...

Descripción completa

Detalles Bibliográficos
Autores principales: Adomavicius, Tomas, Guaita, Margherita, Zhou, Yu, Jennings, Martin D., Latif, Zakia, Roseman, Alan M., Pavitt, Graham D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513899/
https://www.ncbi.nlm.nih.gov/pubmed/31086188
http://dx.doi.org/10.1038/s41467-019-10167-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513899/
https://www.ncbi.nlm.nih.gov/pubmed/31086188
http://dx.doi.org/10.1038/s41467-019-10167-3

Ejemplares similares