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The Role of Lofexidine in Management of Opioid Withdrawal

Fear of withdrawal symptoms has been cited by survey respondents as the main reason that they continued to use opioids. Lofexidine is an α(2)-adrenergic agonist that decreases the sympathetic outflow that results in the characteristic symptoms of opioid withdrawal. A structural analog of clonidine,...

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Detalles Bibliográficos
Autores principales: Pergolizzi, Joseph V., Annabi, Hani, Gharibo, Christopher, LeQuang, Jo Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513979/
https://www.ncbi.nlm.nih.gov/pubmed/30565033
http://dx.doi.org/10.1007/s40122-018-0108-7