Circulating miR-103a-3p contributes to angiotensin II-induced renal inflammation and fibrosis via a SNRK/NF-κB/p65 regulatory axis

Although angiotensin II (AngII) is known to cause renal injury and fibrosis, the underlying mechanisms remain poorly characterized. Here we show that hypertensive nephropathy (HN) patients and AngII-infused mice exhibit elevated levels of circulating miR103a-3p. We observe a positive correlation bet...

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Detalles Bibliográficos
Autores principales: Lu, Qiulun, Ma, Zejun, Ding, Ye, Bedarida, Tatiana, Chen, Liming, Xie, Zhonglin, Song, Ping, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513984/
https://www.ncbi.nlm.nih.gov/pubmed/31086184
http://dx.doi.org/10.1038/s41467-019-10116-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513984/
https://www.ncbi.nlm.nih.gov/pubmed/31086184
http://dx.doi.org/10.1038/s41467-019-10116-0

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