Molecular basis for heat desensitization of TRPV1 ion channels

The transient receptor potential vanilloid 1 (TRPV1) ion channel is a prototypical molecular sensor for noxious heat in mammals. Its role in sustained heat response remains poorly understood, because rapid heat-induced desensitization (Dh) follows tightly heat-induced activation (Ah). To understand...

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Detalles Bibliográficos
Autores principales: Luo, Lei, Wang, Yunfei, Li, Bowen, Xu, Lizhen, Kamau, Peter Muiruri, Zheng, Jie, Yang, Fan, Yang, Shilong, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513986/
https://www.ncbi.nlm.nih.gov/pubmed/31086183
http://dx.doi.org/10.1038/s41467-019-09965-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513986/
https://www.ncbi.nlm.nih.gov/pubmed/31086183
http://dx.doi.org/10.1038/s41467-019-09965-6

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