Temporal dependence of shifts in mu opioid receptor mobility at the cell surface after agonist binding observed by single-particle tracking

Agonist binding to the mu opioid receptor (MOR) results in conformational changes that allow recruitment of G-proteins, activation of downstream effectors and eventual desensitization and internalization, all of which could affect receptor mobility. The present study employed single particle trackin...

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Detalles Bibliográficos
Autores principales: Metz, Marissa J., Pennock, Reagan L., Krapf, Diego, Hentges, Shane T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514008/
https://www.ncbi.nlm.nih.gov/pubmed/31086197
http://dx.doi.org/10.1038/s41598-019-43657-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514008/
https://www.ncbi.nlm.nih.gov/pubmed/31086197
http://dx.doi.org/10.1038/s41598-019-43657-x

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