Identifying Novel Copy Number Variants in Azoospermia Factor Regions and Evaluating Their Effects on Spermatogenic Impairment

Microdeletions in Y-chromosomal azoospermia factor (AZF) regions have been regarded as the risk factor of spermatogenic failure (SF). However, AZF-linked duplications or complex copy number variants (CNVs) (deletion + duplication) were rarely studied. In this study, we performed multiplex ligation-d...

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Detalles Bibliográficos
Autores principales: Zhou, Ran, Cheng, Jian, Ma, Dingyuan, Tan, Jianxin, Wang, Yuguo, Hu, Ping, Xu, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514098/
https://www.ncbi.nlm.nih.gov/pubmed/31134133
http://dx.doi.org/10.3389/fgene.2019.00427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514098/
https://www.ncbi.nlm.nih.gov/pubmed/31134133
http://dx.doi.org/10.3389/fgene.2019.00427

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