Cholesterol and Cardiolipin Importance in Local Anesthetics–Membrane Interactions: The Langmuir Monolayer Study

Local anesthetics (LAs) are known to act on membrane level; however, the molecular mechanism of their activity is still not fully understood. One hypothesis holds that these drugs can incorporate into lipid membrane of nerve cells and in this way change conformation of channel proteins responsible f...

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Detalles Bibliográficos
Autores principales: Mildner, Justyna, Wnętrzak, Anita, Dynarowicz-Latka, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514108/
https://www.ncbi.nlm.nih.gov/pubmed/30506104
http://dx.doi.org/10.1007/s00232-018-0055-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514108/
https://www.ncbi.nlm.nih.gov/pubmed/30506104
http://dx.doi.org/10.1007/s00232-018-0055-6

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