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Cholesterol and Cardiolipin Importance in Local Anesthetics–Membrane Interactions: The Langmuir Monolayer Study
Local anesthetics (LAs) are known to act on membrane level; however, the molecular mechanism of their activity is still not fully understood. One hypothesis holds that these drugs can incorporate into lipid membrane of nerve cells and in this way change conformation of channel proteins responsible f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514108/ https://www.ncbi.nlm.nih.gov/pubmed/30506104 http://dx.doi.org/10.1007/s00232-018-0055-6 |