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Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures

Pathogens face varying microenvironments in vivo, but suitable experimental systems and analysis tools to dissect how three-dimensional (3D) tissue environments impact pathogen spread are lacking. Here we develop an Integrative method to Study Pathogen spread by Experiment and Computation within Tis...

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Detalles Bibliográficos
Autores principales: Imle, Andrea, Kumberger, Peter, Schnellbächer, Nikolas D., Fehr, Jana, Carrillo-Bustamante, Paola, Ales, Janez, Schmidt, Philip, Ritter, Christian, Godinez, William J., Müller, Barbara, Rohr, Karl, Hamprecht, Fred A., Schwarz, Ulrich S., Graw, Frederik, Fackler, Oliver T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514199/
https://www.ncbi.nlm.nih.gov/pubmed/31086185
http://dx.doi.org/10.1038/s41467-019-09879-3