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Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

INTRODUCTION: Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues in pigmented rabbits. METHODS: The anterior r...

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Detalles Bibliográficos
Autores principales: Shinno, Keisuke, Kurokawa, Kazuya, Kozai, Seiko, Kawamura, Akio, Inada, Katsuhiro, Tokushige, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514203/
https://www.ncbi.nlm.nih.gov/pubmed/30891685
http://dx.doi.org/10.1007/s40123-019-0180-z