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Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population

Genetic polymorphism of drug metabolizing enzymes and transporters may influence drug response. The frequency varies substantially between ethnicities thus having implications on appropriate selection and dosage of various drugs in different populations. The distribution of genetic polymorphisms in...

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Detalles Bibliográficos
Autores principales: Afsar, Nasir Ali, Bruckmueller, Henrike, Werk, Anneke Nina, Nisar, Muhammad Kashif, Ahmad, H. R., Cascorbi, Ingolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514210/
https://www.ncbi.nlm.nih.gov/pubmed/31086207
http://dx.doi.org/10.1038/s41598-019-43736-z