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Clinical and Biological Significance of ESR1 Gene Alteration and Estrogen Receptors Isoforms Expression in Breast Cancer Patients

The amplification of estrogen receptor alpha (ERα) encoded by the ESR1 gene has been described as having a prognostic role in breast cancer patients. However, increased dosage of the ESR1 gene (tested by real-time PCR) is also observed in ER-negative breast cancers, which might suggest the expressio...

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Detalles Bibliográficos
Autores principales: Nagel, Anna, Szade, Jolanta, Iliszko, Mariola, Elzanowska, Julia, Welnicka-Jaskiewicz, Marzena, Skokowski, Jaroslaw, Stasilojc, Grzegorz, Bigda, Jacek, Sadej, Rafal, Zaczek, Anna, Markiewicz, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514554/
https://www.ncbi.nlm.nih.gov/pubmed/30995757
http://dx.doi.org/10.3390/ijms20081881