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The Origin and Evolution of Release Factors: Implications for Translation Termination, Ribosome Rescue, and Quality Control Pathways

The evolution of release factors catalyzing the hydrolysis of the final peptidyl-tRNA bond and the release of the polypeptide from the ribosome has been a longstanding paradox. While the components of the translation apparatus are generally well-conserved across extant life, structurally unrelated r...

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Detalles Bibliográficos
Autores principales: Burroughs, A. Maxwell, Aravind, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514570/
https://www.ncbi.nlm.nih.gov/pubmed/31018531
http://dx.doi.org/10.3390/ijms20081981