Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer

DUSP6/MKP3 is a dual-specific phosphatase that regulates extracellular regulated kinase ERK1/2 and ERK5 activity, with an increasingly recognized role as tumor suppressor. In silico studies from Gene expression Omnibus (GEO) and Cancer Genome atlas (TCGA) databases reveal poor prognosis in those Non...

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Detalles Bibliográficos
Autores principales: Moncho-Amor, Verónica, Pintado-Berninches, Laura, Ibañez de Cáceres, Inmaculada, Martín-Villar, Ester, Quintanilla, Miguel, Chakravarty, Probir, Cortes-Sempere, María, Fernández-Varas, Beatriz, Rodriguez-Antolín, Carlos, de Castro, Javier, Sastre, Leandro, Perona, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514584/
https://www.ncbi.nlm.nih.gov/pubmed/31027181
http://dx.doi.org/10.3390/ijms20082036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514584/
https://www.ncbi.nlm.nih.gov/pubmed/31027181
http://dx.doi.org/10.3390/ijms20082036

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