Cargando…

Impact of Small Molecules on Intermolecular G-Quadruplex Formation

We performed single molecule studies to investigate the impact of several prominent small molecules (the oxazole telomestatin derivative L2H2-6OTD, pyridostatin, and Phen-DC(3)) on intermolecular G-quadruplex (i-GQ) formation between two guanine-rich DNA strands that had 3-GGG repeats in one strand...

Descripción completa

Detalles Bibliográficos
Autores principales: Gyawali, Prabesh, GC, Keshav, Ma, Yue, Abeysirigunawardena, Sanjaya, Nagasawa, Kazuo, Balci, Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514588/
https://www.ncbi.nlm.nih.gov/pubmed/31010019
http://dx.doi.org/10.3390/molecules24081570