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Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding

Avian coronaviruses, including infectious bronchitis virus (IBV), are important respiratory pathogens of poultry. The heavily glycosylated IBV spike protein is responsible for binding to host tissues. Glycosylation sites in the spike protein are highly conserved across viral genotypes, suggesting an...

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Detalles Bibliográficos
Autores principales: Parsons, Lisa M., Bouwman, Kim M., Azurmendi, Hugo, de Vries, Robert P., Cipollo, John F., Verheije, Monique H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514631/
https://www.ncbi.nlm.nih.gov/pubmed/30902814
http://dx.doi.org/10.1074/jbc.RA119.007532