The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Restores Cardiomyocyte Contractility in a Rat Model of Early Diabetes

In early diabetes, hyperglycemia and the associated metabolic dysregulation promote early changes in the functional properties of cardiomyocytes, progressively leading to the appearance of the diabetic cardiomyopathy phenotype. Recently, the interplay between histone acetyltransferases (HAT) and his...

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Detalles Bibliográficos
Autores principales: Bocchi, Leonardo, Motta, Benedetta M., Savi, Monia, Vilella, Rocchina, Meraviglia, Viviana, Rizzi, Federica, Galati, Serena, Buschini, Annamaria, Lazzaretti, Mirca, Pramstaller, Peter P., Rossini, Alessandra, Stilli, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514644/
https://www.ncbi.nlm.nih.gov/pubmed/31014028
http://dx.doi.org/10.3390/ijms20081873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514644/
https://www.ncbi.nlm.nih.gov/pubmed/31014028
http://dx.doi.org/10.3390/ijms20081873

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