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Energy Metabolism in the Failing Right Ventricle: Limitations of Oxygen Delivery and the Creatine Kinase System

Pulmonary arterial hypertension (PAH) results in hypertrophic remodeling of the right ventricle (RV) to overcome increased pulmonary pressure. This increases the O(2) consumption of the myocardium, and without a concomitant increase in energy generation, a mismatch with demand may occur. Eventually,...

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Detalles Bibliográficos
Autores principales: Fowler, Ewan D., Hauton, David, Boyle, John, Egginton, Stuart, Steele, Derek S., White, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514649/
https://www.ncbi.nlm.nih.gov/pubmed/31013688
http://dx.doi.org/10.3390/ijms20081805