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Fused Heterocyclic Systems with an s-Triazine Ring. 34. Development of a Practical Approach for the Synthesis of 5-Aza-isoguanines

Purine isosteres present excellent opportunities in drug design and development. Using isosteres of natural purines as scaffolds for the construction of new therapeutic agents has been a valid strategy of medicinal chemistry. Inspired by the similarity to isoguanine, we attempted to develop a practi...

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Detalles Bibliográficos
Autores principales: Junaid, Ahmad, Lim, Felicia Phei Lin, Zhou, Yvonne Peijun, Chui, Wai Keung, Dolzhenko, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514761/
https://www.ncbi.nlm.nih.gov/pubmed/31013786
http://dx.doi.org/10.3390/molecules24081453