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Blast Transformation in Myeloproliferative Neoplasms: Risk Factors, Biological Findings, and Targeted Therapeutic Options

Myeloproliferative neoplasms represent a heterogenous group of disorders of the hematopoietic stem cell, with an intrinsic risk of evolution into acute myeloid leukemia. The frequency of leukemic evolution varies according to myeloproliferative neoplasms subtype. It is highest in primary myelofibros...

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Detalles Bibliográficos
Autores principales: Iurlo, Alessandra, Cattaneo, Daniele, Gianelli, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514804/
https://www.ncbi.nlm.nih.gov/pubmed/31013941
http://dx.doi.org/10.3390/ijms20081839