Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers

HIV-1 integrase (HIV-1 IN) is an enzyme produced by the HIV-1 virus that integrates genetic material of the virus into the DNA of infected human cells. HIV-1 IN acts as a key component of the Retroviral Pre-Integration Complex (PIC). Protein dynamics could play an important role during the catalysis...

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Detalles Bibliográficos
Autores principales: Park, Jae-Hyun, Yun, Ji-Hye, Shi, Yingchen, Han, Jeongmin, Li, Xuanxuan, Jin, Zeyu, Kim, Taehee, Park, Jaehyun, Park, Sehan, Liu, Haiguang, Lee, Weontae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514806/
https://www.ncbi.nlm.nih.gov/pubmed/31010024
http://dx.doi.org/10.3390/ijms20081943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514806/
https://www.ncbi.nlm.nih.gov/pubmed/31010024
http://dx.doi.org/10.3390/ijms20081943

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