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Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers
HIV-1 integrase (HIV-1 IN) is an enzyme produced by the HIV-1 virus that integrates genetic material of the virus into the DNA of infected human cells. HIV-1 IN acts as a key component of the Retroviral Pre-Integration Complex (PIC). Protein dynamics could play an important role during the catalysis...
Autores principales: | Park, Jae-Hyun, Yun, Ji-Hye, Shi, Yingchen, Han, Jeongmin, Li, Xuanxuan, Jin, Zeyu, Kim, Taehee, Park, Jaehyun, Park, Sehan, Liu, Haiguang, Lee, Weontae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514806/ https://www.ncbi.nlm.nih.gov/pubmed/31010024 http://dx.doi.org/10.3390/ijms20081943 |
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