Cargando…

Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling

Mitogen-activated protein kinases (MAPK): Erk1 and Erk2 are key players in negative-feedback regulation of fibroblast growth factor (FGF) signaling. Upon activation, Erk1 and Erk2 directly phosphorylate FGF receptor 1 (FGFR1) at a specific serine residue in the C-terminal part of the receptor, subst...

Descripción completa

Detalles Bibliográficos
Autores principales: Zakrzewska, Malgorzata, Opalinski, Lukasz, Haugsten, Ellen M., Otlewski, Jacek, Wiedlocha, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514807/
https://www.ncbi.nlm.nih.gov/pubmed/31013829
http://dx.doi.org/10.3390/ijms20081826