Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells

Antiestrogens (AEs) are widely used for treatment of estrogen receptor alpha (ERα)-positive breast cancer, but display variable degrees of partial agonism in estrogen target tissues and breast cancer (BC) cells. The fact that BC cells resistant to selective ER modulators (SERMs) like tamoxifen (Tam)...

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Detalles Bibliográficos
Autores principales: Traboulsi, Tatiana, El Ezzy, Mohamed, Dumeaux, Vanessa, Audemard, Eric, Mader, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514857/
https://www.ncbi.nlm.nih.gov/pubmed/30190545
http://dx.doi.org/10.1038/s41388-018-0468-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514857/
https://www.ncbi.nlm.nih.gov/pubmed/30190545
http://dx.doi.org/10.1038/s41388-018-0468-9

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