Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy

Intratumoral electroporation-mediated IL-12 gene therapy (IT-pIL12/EP) has been shown to be safe and effective in clinical trials, demonstrating systemic antitumor effects with local delivery of this potent cytokine. We recently optimized our IL-12 gene delivery platform to increase transgene expres...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Anandaroop, Wright, Jocelyn, Shirley, Shawna, Canton, David A., Burkart, Christoph, Connolly, Richard J., Campbell, Jean S., Pierce, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514882/
https://www.ncbi.nlm.nih.gov/pubmed/30323352
http://dx.doi.org/10.1038/s41434-018-0044-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514882/
https://www.ncbi.nlm.nih.gov/pubmed/30323352
http://dx.doi.org/10.1038/s41434-018-0044-5

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