DNA Methylation Contributes to the Differential Expression Levels of Mecp2 in Male Mice Neurons and Astrocytes

Methyl CpG binding protein-2 (MeCP2) isoforms (E1 and E2) are important epigenetic regulators in brain cells. Accordingly, MeCP2 loss- or gain-of-function mutation causes neurodevelopmental disorders, including Rett syndrome (RTT), MECP2 duplication syndrome (MDS), and autism spectrum disorders (ASD...

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Detalles Bibliográficos
Autores principales: Liyanage, Vichithra R.B., Olson, Carl O., Zachariah, Robby M., Davie, James R., Rastegar, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514911/
https://www.ncbi.nlm.nih.gov/pubmed/31013990
http://dx.doi.org/10.3390/ijms20081845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514911/
https://www.ncbi.nlm.nih.gov/pubmed/31013990
http://dx.doi.org/10.3390/ijms20081845

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