Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Aminobiphenyl-Modified DNA

Bulky organic carcinogens are activated in vivo and subsequently react with nucleobases of cellular DNA to produce adducts. Some of these DNA adducts exist in multiple conformations that are slowly interconverted to one another. Different conformations have been implicated in different mutagenic and...

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Detalles Bibliográficos
Autores principales: Cai, Ang, Bian, Ke, Chen, Fangyi, Tang, Qi, Carley, Rachel, Li, Deyu, Cho, Bongsup P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514942/
https://www.ncbi.nlm.nih.gov/pubmed/31009995
http://dx.doi.org/10.3390/molecules24081566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514942/
https://www.ncbi.nlm.nih.gov/pubmed/31009995
http://dx.doi.org/10.3390/molecules24081566

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