TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca(2+) Sensitivity but Not Significance of PI(4,5)P(2)

Transient receptor potential melastatin member 4 (TRPM4) and 5 (TRPM5) channels are Ca(2+)-activated nonselective cation channels. Intracellular Ca(2+) is the most important regulator for them to open, though PI(4,5)P(2), a membrane phosphoinositide, has been reported to regulate their Ca(2+)-sensit...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Soichiro, Tanimoto, Akira, Iwasa, Shinsuke, Otsuguro, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514954/
https://www.ncbi.nlm.nih.gov/pubmed/31022885
http://dx.doi.org/10.3390/ijms20082012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514954/
https://www.ncbi.nlm.nih.gov/pubmed/31022885
http://dx.doi.org/10.3390/ijms20082012

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