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TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca(2+) Sensitivity but Not Significance of PI(4,5)P(2)
Transient receptor potential melastatin member 4 (TRPM4) and 5 (TRPM5) channels are Ca(2+)-activated nonselective cation channels. Intracellular Ca(2+) is the most important regulator for them to open, though PI(4,5)P(2), a membrane phosphoinositide, has been reported to regulate their Ca(2+)-sensit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514954/ https://www.ncbi.nlm.nih.gov/pubmed/31022885 http://dx.doi.org/10.3390/ijms20082012 |