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Synthesis, Antibacterial Activities, Mode of Action and Acute Toxicity Studies of New Oxazolidinone-Fluoroquinolone Hybrids

To combat bacterial resistance, a series of new oxazolidinone-fluoroquinolone hybrids have been synthesized and characterized. All synthetic hybrids were preliminarily evaluated for their in vitro antibacterial activities against 6 standard strains and 3 clinical isolates. The majority of hybrids di...

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Detalles Bibliográficos
Autores principales: Liu, Lili, Shao, Liping, Li, Jing, Cui, Haifeng, Li, Bing, Zhou, Xuzheng, Lv, Pengyue, Zhang, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514978/
https://www.ncbi.nlm.nih.gov/pubmed/31027311
http://dx.doi.org/10.3390/molecules24081641