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Biodistribution of [(11)C]-Metformin and mRNA Expression of Placentae Metformin Transporters in the Pregnant Chinchilla

BACKGROUND: While metformin is the first-line pharmacological treatment of diabetes mellitus type 2, this drug is not considered safe to use in pregnant women because of its unknown consequences for the fetus. In this study, we aimed to investigate the biodistribution of metformin in the pregnant ch...

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Detalles Bibliográficos
Autores principales: Overgaard, Maria Dahl, Duvald, Christina Søndergaard, Vendelbo, Mikkel Holm, Pedersen, Steen Bønløkke, Jakobsen, Steen, Alstrup, Aage Kristian Olsen, Mikkelsen, Emmeli, Ovesen, Per Glud, Pedersen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515019/
https://www.ncbi.nlm.nih.gov/pubmed/31182937
http://dx.doi.org/10.1155/2019/9787340