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The Emerging Perspective of Morphine Tolerance: MicroRNAs

Morphine has unfavorable side effects including analgesic tolerance. Morphine tolerance counteracts analgesic efficacy and drives dose escalation. The mechanisms underlying morphine tolerance remain disputed, which has prevented the development of therapies to maximize and sustain analgesic efficacy...

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Detalles Bibliográficos
Autores principales: Zhang, Teng J., Qiu, Yong, Hua, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515020/
https://www.ncbi.nlm.nih.gov/pubmed/31182985
http://dx.doi.org/10.1155/2019/9432965