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Lipophilicity as a Central Component of Drug-Like Properties of Chalchones and Flavonoid Derivatives

Lipophilcity is an important physico-chemical parameter that influences membrane transport and binding ability to action. Migration distance following complete elution of compounds was used to calculate different lipophilicity-related parameters. The aim of this study is to show that lipophilicity i...

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Detalles Bibliográficos
Autores principales: Constantinescu, Teodora, Lungu, Claudiu Nicolae, Lung, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515054/
https://www.ncbi.nlm.nih.gov/pubmed/30999606
http://dx.doi.org/10.3390/molecules24081505