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Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease

Dipeptidyl peptidase IV (DPPIV) inhibitors are antidiabetic agents that exert renoprotective actions independently of glucose lowering. Cardiac dysfunction is one of the main outcomes of chronic kidney disease (CKD); however, the effects of DPPIV inhibition on cardiac impairment during CKD progressi...

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Detalles Bibliográficos
Autores principales: Beraldo, Juliana Isa, Benetti, Acaris, Borges-Júnior, Flávio Araújo, Arruda-Junior, Daniel F., Martins, Flavia Letícia, Jensen, Leonardo, Dariolli, Rafael, Shimizu, Maria Heloisa, Seguro, Antonio C., Luchi, Weverton M., Girardi, Adriana C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515057/
https://www.ncbi.nlm.nih.gov/pubmed/31010001
http://dx.doi.org/10.3390/ijms20081940