Inhibitory Effect of Berberine on Broiler P-glycoprotein Expression and Function: In Situ and In Vitro Studies

Overcoming P-glycoprotein (P-gp) efflux is a strategy to improve the absorption and pharmacokinetics of its substrate drugs. Berberine inhibits P-gp and thereby increases the bioavailability of the P-gp substrate digoxin in rodents. However, the effects of berberine on P-gp in chickens are still unc...

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Detalles Bibliográficos
Autores principales: Zhang, Yujuan, Guo, Li, Huang, Jinhu, Sun, Yong, He, Fang, Zloh, Mire, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515058/
https://www.ncbi.nlm.nih.gov/pubmed/31013627
http://dx.doi.org/10.3390/ijms20081966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515058/
https://www.ncbi.nlm.nih.gov/pubmed/31013627
http://dx.doi.org/10.3390/ijms20081966

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