Cognizance of Molecular Methods for the Generation of Mutagenic Phage Display Antibody Libraries for Affinity Maturation

Antibodies leverage on their unique architecture to bind with an array of antigens. The strength of interaction has a direct relation to the affinity of the antibodies towards the antigen. In vivo affinity maturation is performed through multiple rounds of somatic hypermutation and selection in the...

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Detalles Bibliográficos
Autores principales: Lim, Chia Chiu, Choong, Yee Siew, Lim, Theam Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515083/
https://www.ncbi.nlm.nih.gov/pubmed/30991723
http://dx.doi.org/10.3390/ijms20081861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515083/
https://www.ncbi.nlm.nih.gov/pubmed/30991723
http://dx.doi.org/10.3390/ijms20081861

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