Involvement of p38 Activation and Mitochondria in Death of Human Leukemia Cells Induced by an Agonistic Human Monoclonal Antibody Fab Specific to TRAIL Receptor 1

The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces cancer cell death with minimal damage to normal cells; however, some cancer cells are resistant to TRAIL. TRAIL resistance may be overcome by agonistic antibodies to TRAIL receptors. In this study, we report the toxic effect...

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Detalles Bibliográficos
Autores principales: Lee, You-Ri, Hwang, Eunjoo, Jang, Young-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515105/
https://www.ncbi.nlm.nih.gov/pubmed/31013630
http://dx.doi.org/10.3390/ijms20081967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515105/
https://www.ncbi.nlm.nih.gov/pubmed/31013630
http://dx.doi.org/10.3390/ijms20081967

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