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Improvement of l-Leucine Production in Corynebacterium glutamicum by Altering the Redox Flux
The production of l-leucine was improved by the disruption of ltbR encoding transcriptional regulator and overexpression of the key genes (leuAilvBNCE) of the l-leucine biosynthesis pathway in Corynebacterium glutamicum XQ-9. In order to improve l-leucine production, we rationally engineered C. glut...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515235/ https://www.ncbi.nlm.nih.gov/pubmed/31022947 http://dx.doi.org/10.3390/ijms20082020 |