Synergistic Effect of Low Molecular Weight Polyethylenimine and Polyethylene Glycol Components in Dynamic Nonviral Vector Structure, Toxicity, and Transfection Efficiency

When studying polyethylenimine derivatives as nonviral vectors for gene delivery, among the important issues to be addressed are high toxicity, low transfection efficiency, and nucleic acid polyplex condensation. The molecular weight of polyethylenimine, PEGylation, biocompatibility and, also, supra...

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Detalles Bibliográficos
Autores principales: Craciun, Bogdan Florin, Gavril, Gabriela, Peptanariu, Dragos, Ursu, Laura Elena, Clima, Lilia, Pinteala, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515267/
https://www.ncbi.nlm.nih.gov/pubmed/31013863
http://dx.doi.org/10.3390/molecules24081460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515267/
https://www.ncbi.nlm.nih.gov/pubmed/31013863
http://dx.doi.org/10.3390/molecules24081460

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