Microwave-Assisted Synthesis of Trazodone and Its Derivatives as New 5-HT(1A) Ligands: Binding and Docking Studies

Trazodone, a well-known antidepressant drug widely used throughout the world, works as a 5-hydroxytryptamine (5-HT(2)) and α(1)-adrenergic receptor antagonist and a serotonin reuptake inhibitor. Our research aimed to develop a new method for the synthesis of trazodone and its derivatives. In the kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaśkowska, Jolanta, Zaręba, Przemysław, Śliwa, Paweł, Pindelska, Edyta, Satała, Grzegorz, Majka, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515286/
https://www.ncbi.nlm.nih.gov/pubmed/31018618
http://dx.doi.org/10.3390/molecules24081609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515286/
https://www.ncbi.nlm.nih.gov/pubmed/31018618
http://dx.doi.org/10.3390/molecules24081609

Ejemplares similares