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Microwave-Assisted Synthesis of Trazodone and Its Derivatives as New 5-HT(1A) Ligands: Binding and Docking Studies
Trazodone, a well-known antidepressant drug widely used throughout the world, works as a 5-hydroxytryptamine (5-HT(2)) and α(1)-adrenergic receptor antagonist and a serotonin reuptake inhibitor. Our research aimed to develop a new method for the synthesis of trazodone and its derivatives. In the kno...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515286/ https://www.ncbi.nlm.nih.gov/pubmed/31018618 http://dx.doi.org/10.3390/molecules24081609 |