RSK2-Mediated ELK3 Activation Enhances Cell Transformation and Breast Cancer Cell Growth by Regulation of c-fos Promoter Activity

Ribosomal S6 kinase 2 (RSK2), regulated by Ras/Raf/MEKs/ERKs, transmits upstream activation signals to downstream substrates including kinases and transcription and epigenetic factors. We observed that ELK members, including ELK1, 3, and 4, highly interacted with RSK2. We further observed that the R...

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Detalles Bibliográficos
Autores principales: Yoo, Sun-Mi, Lee, Cheol-Jung, An, Hyun-Jung, Lee, Joo Young, Lee, Hye Suk, Kang, Han Chang, Cho, Sung-Jun, Kim, Seung-Min, Park, Juhee, Kim, Dae Joon, Cho, Yong-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515335/
https://www.ncbi.nlm.nih.gov/pubmed/31018569
http://dx.doi.org/10.3390/ijms20081994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515335/
https://www.ncbi.nlm.nih.gov/pubmed/31018569
http://dx.doi.org/10.3390/ijms20081994

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