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An In Silico Model for Predicting Drug-Induced Hepatotoxicity

As one of the leading causes of drug failure in clinical trials, drug-induced liver injury (DILI) seriously impeded the development of new drugs. Assessing the DILI risk of drug candidates in advance has been considered as an effective strategy to decrease the rate of attrition in drug discovery. Re...

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Detalles Bibliográficos
Autores principales: He, Shuaibing, Ye, Tianyuan, Wang, Ruiying, Zhang, Chenyang, Zhang, Xuelian, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515336/
https://www.ncbi.nlm.nih.gov/pubmed/30999595
http://dx.doi.org/10.3390/ijms20081897